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Furthermore, genetically proxied effects of GLP-1R-based agonists were causally associated with an improved metabolic risk profile

GLP-1s may be risky for older adults

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[7] [11] In a Phase 2 randomised controlled trial published in The New England Journal of Medicine (Jastreboff et al., 2023), retatrutide demonstrated substantial reductions in body weight over 48 weeks

Over weeks of daily or weekly injections, those errors compound significantly

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