Copper Chelation and Delivery At the most fundamental level, GHK functions as a copper chelator and delivery system - the tripeptide binds Cu with exceptionally high affinity (binding constant approximately 10 M, among the highest known for biological copper chelators), forming a square planar coordination complex where the copper ion is coordinated by the nitrogen atoms of the terminal amino group, the two peptide bonds, and the imidazole nitrogen of histidine
Strong antioxidant qualities of glutathione are well known for assisting in the neutralization of negative free radicals and lowering oxidative stress
For example, NS nurses in Poland showed increased PER1 expression, especially after 15 years of NSW 205
GHK-Cu antioxidant approach: Upregulates endogenous antioxidant enzymes (SOD, catalase, glutathione peroxidase) rather than providing antioxidants directly
Supports Immune & Detox Health - Glutathione is traditionally valued for its role in immune system balance and natural detoxification support as part of a daily wellness routine
This direct approach ensures better absorption and effectiveness
