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It is thought that its primary action is on the liver and it was demonstrated that it inhibits hepatic gluconeogenesis both in vitro and in vivo in a redox-dependent manner without concomitant increases in plasma insulin concentrations

[PubMed]52

If you do not have weekend support, choose whatever day gives you the most backup during the 48 hours following your injection

Card Fail Rev 3:711 Usman MS, Siddiqi TJ, Memon MM, Khan MS, Rawasia WF, Talha Ayub M, Sreenivasan J, Golzar Y (2018) Sodium-glucose co-transporter 2 inhibitors and cardiovascular outcomes: a systematic review and meta-analysis

Most patients experience constipation most noticeably during dose escalationwhen your dose may need to go up over the first month of treatment