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Genazzani 2007

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15 , e1007889 (2019)

May 21, 2025

These findings should be overseen with glutamate as the major excitatory neurotransmitter in the central nervous system (i.e., cognitive functions such as learning and memory in the brain [200], the precursor of major inhibitory neurotransmitter GABA) but excitotoxic neuronal death as a direct result of high concentrations [201], and tight physiologic range that should be maintained [59]

Dosage: 0.25 to 0.5 mg daily Administration: Subcutaneous injection 1 to 2 inches from lateral epicondyle Frequency: Once daily, some split into twice daily Duration: 4 to 8 weeks for acute injuries, 8 to 12 weeks for chronic Timing: Evening injection may align with natural repair cycles during sleep Starting Conservative Beginning with lower doses and gradually increasing allows you to assess your response while minimizing any potential issues