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A Phase 2 trial (NCT01311518) was designed to test RGN-352 in ~75 heart attack patients, but was placed on FDA clinical hold in 2011 due to manufacturing (GMP) compliance issues at the contract site not safety concerns with the drug itself

Nursing mothers should complete breastfeeding before starting treatment

The ability of bacteriostatic water to inhibit bacterial growth, thus allowing safer multiple uses from a single vial, makes it an indispensable tool in medicine.

KPV is derived from alpha-MSH but does not bind melanocortin receptors (MC1R, MC3R, MC5R)

Duration: Preclinical studies have lasted about 4 weeks on average

The standard NHS maintenance schedule for a non-dietary cause is a 1mg injection every two to three months for life