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Approximately 30 million Americans and an estimated 425 million people worldwide have diabetes, and nearly 24 percent of Americans with diabetes or more than 7 million people are undiagnosed

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Int J Environ Res Public Health 17(10):3589 Natalicchio A, Marrano N, Biondi G, Montedoro A, Grazie GL, Gioia LD, Guarini F, Borrelli A, Cignarelli A, Perrini S, Laviola L, Giorgino F (2021) 241-OR: effects of antidiabetes therapies on irisin levels in type 2 diabetes patients