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Importantly, the medication reduced major cardiovascular events by 20% compared to placebo

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151 For the NADPH-synthesis enzymes involved in anapleurotic reactions, including IDH1/2, ME1/2/3, and CPT1/2, the targeting inhibitors are also being extensively developed

Kidney impairment Patients with kidney impairment should use the medication with caution due to the risk of dehydration from the gastrointestinal side effects