It does this by acting on a number of hormone pathways implicated in appetite and metabolism
Cocaine Only limited clinical evidence is available for GLP-1RAs in cocaine misuse: a small ( N = 13) proof-of-concept trial across 2 days showed that exenatide compared with placebo did not reduce the number of self-administered cocaine infusions 115 , while a case series of 3 individuals with cocaine-use disorder highlighted the feasibility and safety of using the same drug over 6 weeks, although no efficacy measures were reported 116
The team also pointed out the likelihood of abuse among patients with diagnosed eating disorders and children and adolescents involved in competitive sports like wrestling, martial arts, gymnastics and ballet
What do these trial results mean in practical terms
Discontinuation typically leads to weight regain unless lifestyle factors have substantially shifted in the meantime, which is why we work on those alongside the medication, not after
Insert the needle at a 90-degree angle (straight in)
