Most safety data comes from mouse studies conducted by Thomas Burris and colleagues at Saint Louis University and later the University of Florida
GI side effects from Retatrutide can cause fluid loss
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Advanced Stack Protocol (Fat Loss / Mitochondrial Optimization) For those already hormonally optimized and looking to maximize metabolic output, I recommend the NAD+/MOTS-C/5-Amino-1MQ blend: Vial composition: 100 mg NAD+ / 10 mg MOTS-C / 10 mg 5-Amino-1MQ Reconstitution: 2 mL bacteriostatic water Dose: 500 mcg / 1 mg per injection (10 units on insulin syringe) Timing: AM Frequency: 5 days on, 2 days off Cycle length: 8 weeks on, 8 weeks off What NOT to Do Daily doses of1520 mg (higher doses do NOT consistently produce better outcomes and may increase fatigue, nausea, and injection site reactions) Long continuous use without cycling on and of Stacking multiple AMPK agonists blindly (be especially careful when combining MOTS-C with Metformin or Berberine without guidance) Less is more
BPC-157 is generally described with more frequent administration, while TB-500 is often described with a higher initial "loading" frequency followed by a lower maintenance frequency
In addition, vitamin B12 is needed to produce myelin and is important for axon and nerve development