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Combined, these effects disrupt normal cyclic hormone patterns, change feedback to the hypothalamus and pituitary, and can result in irregular cycles, low sperm quality, or anovulation

doi: 10.1159/000494799 35 VerplaetseTLMcKeeSA

The available ESSENCE publication does not include individual participant data (IPD), multivariable models that adjust for weight loss, or mediation analyses to estimate effects independently of body weight or other metabolic variables [7]

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These symptoms are typically temporary and should subside as your body adapts