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The abundance of one such family, Ruminococcaceae , is positively correlated with thiamine intake in humans

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Aggregation rather than shear is the specific risk with an amylin-family sequence: the prolines at positions 25, 28 and 29 reduce fibrillation propensity relative to native amylin but do not eliminate it, so inspect the solution against a light source for haze, opalescence or filaments before use