So, in 2023, after reading about the benefits of GLP-1 medications like semaglutide and tirzepatide, she found a health care professional who agreed to prescribe her one
trade name: Poncho Votivo) and a pyrethroid (primary active ingredient: esfenvalerate
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The intent with propensity-score matching was to identify control patients that were just as likely to have been prescribed GLP-1s as the treatment cohort based on a wide range of observed covariates, and it is reasonable to assume that such patients would be pursuing additional therapies over the study duration that would improve their weight and HbA1c as well
However, the ~16% difference in elevation of muscle carnosine between the two formulations did not reach statistical significance, perhaps due to the small sample size or the short supplementation period