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Adoption is concentrated among women aged 5064 in higher-income households, giving this group an outsized influence on emerging trends in spending, fitness, and lifestyle choices (33)

The unfortunate truth is that big risk signals (lets say the kind you get from drinking antifreeze) can be spotted from the anecdotal experience of people in the world just trying things, but small-but-serious risk signals (lets say cardiovascular disease with tofacitinib) are really hard to identify without a proper trial or a proper observational study

6A) and a lower level of ATP (Fig

Tetrahedron 54 , 20592074 (1998)