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A study from the International Journal of Epidemiology established an even more dire connection

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MENSTRUAL & SEXUAL Heavy or painful periods Irregular periods Ovarian cysts Fibroids Decreased sex drive MENTAL Mood swings Irritability Anxiety Depression Cravings PHYSICAL Breast tenderness Bloating, swelling, or fluid retention Headaches or migraines Weight gain Insomnia or fatigue EFFECTIVE Proven to support healthy estrogen balance, directly targeting the internal root cause of hormonal acne driven by high estrogen

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Another obstacle to clinical translation involves optimization of delivery methods for the therapeutics