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The triple agonist mechanism appears to match or slightly exceed tirzepatide for blood sugar management , likely because the glucagon component, while it can raise blood sugar in isolation, works synergistically with GLP-1 and GIP activation to produce a net positive effect on glucose regulation

These side effects may also affect mood and energy levels

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GLP-1-based treatments may be recommended for individuals who: Not all patients are candidates for GLP-1/GIP-based weight loss treatments

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