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It is required for numerous biological processes, including red blood cell formation, homocysteine metabolism and the methylation of myelin, which forms the protective sheath surrounding nerves

[DOI] [PubMed] [Google Scholar] 5.Straight and paired helical filaments in Alzheimer disease have a common structural unit

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On the other hand, PCNA is essential for cell proliferation, and it interacts with various proteins in regulating the cell cycle, DNA replication, and DNA repair process ( BMP2 gene appeared to have a 14-fold greater expression upon EGCG treatment on HuLM cells (Zhang et al., 2010a)