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Science 310 , 847850 (2005)
Meta-analyses sit at the top of the evidence hierarchy in medicine
Avoid them
Mild Nausea or Diarrhea Some people report feeling nauseous or having mild diarrhea after getting B12 injections
LY3437943 (Retatrutide): discovery to clinical proof of concept (triple GLP-1/GIP/glucagon agonist, preclinical mechanism) Nature Reviews Endocrinology (2024) Multi-receptor agonists for metabolic disease (mechanism of GLP-1/GIP/glucagon co-activation) Diabetes Care (2024) Incretin-based therapies: GLP-1, GIP, and glucagon receptor pharmacology (metabolic pathways, energy expenditure) NEJM (2023) Supplementary Material Jastreboff et al
But every citation offered in support of the stack is a study of one compound alone
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