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In the S 2 pocket, an aromatic heterocyclic ring or substituted fused rings are preferred

doi: 10.4155/tde.11.132

Michael Donnino introduced the term gastrointestinal beriberi (63) to describe a distinct clinical entity caused by TD in the gastrointestinal system

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CV risk factors were prevalent: 71% had a history of hypertension, 60% had hyperlipidaemia, and 14% reported current smoking