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Optogenetic activation of the dorsal raphe serotonergic neurons attenuates social and cognitive deficits in prenatal VPA mice To investigate whether ASD-like behavior in prenatal VPA mice is attenuated by the activation of DRN, we implanted an optical fiber in the DRN of TPH2-tTA::TetO-ChR2 tg mice, which is specifically expressed ChR2 in serotonergic neurons (Fig
doi: 10.1001/jama.2016.0287 Summary Keywords GLP-1 - glucagon-like peptide-1, incretin, GLP-1 agonists, hormone, inflammation, anti-inflammation Citation Mehdi SF, Pusapati S, Anwar MS, Lohana D, Kumar P, Nandula SA, Nawaz FK, Tracey K, Yang H, LeRoith D, Brownstein MJ and Roth J (2023) Glucagon-like peptide-1: a multi-faceted anti-inflammatory agent
Heres what you need to know: Yes, they work
The peptides' hypothesized impacts on growth hormone regulation and associated pathways require rigorous investigation to validate their properties and mechanisms
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