The real task is to understand what may be driving it
GromadzinskaJPolanskaKKozlowskaLMikolajewskaKStelmachIJerzynskaJet al
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Metsera also reported MET-097i is well tolerated with a monthly dose after 12 weekly doses
Common adverse effects of Ozempic, as documented in the UK SmPC, include: Gastrointestinal symptoms : nausea, vomiting, diarrhoea, constipation, abdominal pain (very common, affecting more than 1 in 10 patients) Decreased appetite (very common) Hypoglycaemia : when used in combination with insulin or sulphonylureas Gallbladder disorders : including cholelithiasis and cholecystitis Fatigue Injection site reactions : such as bruising or pain Whilst musculoskeletal pain is not formally listed, healthcare professionals should remain vigilant for patient reports and consider the broader context of treatment, including weight loss trajectory, nutritional status, and concurrent medical conditions
Further analysis, including PCA, differential metabolite screening, and pathway enrichment analysis, was conducted using MetaboAnalyst 6.0 ( 51