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Through the production of IL-10 and transforming growth factor-beta (TGF-), T reg s suppressed nearby cytotoxic cells, leading to immune evasion for the tumor [155, 156]

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Furthermore, we used a commercial glycolysis antibody panel to detect Pfkp, Pyruvate kinase M1 and M2 (Pkm1, Pkm2), Hexokinase 1, Hexokinase 2 and Pyruvate dehydrogenase 1 subunit (Pdh) by immunoblot analysis