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Arch Toxicol 89(7):10351044

Although still exploratory, these findings suggest that the Kyn/Trp ratio may warrant further evaluation as a potential marker for risk stratification in longitudinal studies

Brandt KE, Falls KC, Schoenfeld JD, Rodman SN, Gu Z, Zhan F, et al

This approach allows patients to establish baseline responses before introducing more complex protocols

Intra-arterial infusion of nor-NOHA (0.1 mg/min) improves endothelium-dependent vasorelaxation in radial artery following ischemia-reperfusion injury in male patients (average age 65) with coronary artery disease (CAD, n = 12) or CAD and type 2 diabetes (T2D, n = 12) (Kovamees et al., 2014)

Reviewed May 2026