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Systematic administration of exogenous CoQ 10, beginning 3 days prior to the noise insult, has been shown to improve hearing threshold, reducing HC bundle disorientation and SGN loss in the mid-cochlear turn, likely due to lowered noise-induced oxidative stress on the sensorineural tissues

Metformin and insulin, which are commonly used antidiabetic therapies, have certainly prolonged the lives of patients with diabetes (Joya-Galeana et al., 2011

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doi: 10.1046/j.1532-5415.2001.49173.x