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Moreover, the current analysis did not include comparative ROC curves or Net Reclassification Improvement (NRI) statistics with existing clinical or laboratory tools, limiting our ability to fully determine the added diagnostic value of GDF15

253 In multiple myeloma, dual luciferase reporter assay showed that H19 inhibits miR-152-3p to enhance BRD4 expression

however, some developmental biologists believe it has evolved from haemochorial placentation and named it secondary epitheliochorial placentation (5)

Furthermore, GDF15 has been implicated in disorders associated with central sensitization, highlighting its relevance to FM pathophysiology 11

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