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Maintaining balanced IGF-1 + IGFBP-3 levels supports healthy tissue repair without tipping into excessive growth

Particular attention is warranted for diverse populations, including older adults, individuals with advanced renal disease, pregnant patients, and those at risk of lean mass loss during rapid weight reduction

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10.1081/JAS-200038447

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However, the period before the breeding season is characterized by the scarcity of forage in tropical regions and may impair cows reproductive performance and the establishment of pregnancy