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As expected, linagliptin did not increase active GLP-1 levels to control levels in the Gcg RA PDX1Cre mice as the pancreas is not a major contributor to circulating GLP-1

10.1016/j.biomaterials.2012.12.009 Biomaterials 7 CharlierE.DeroyerC.CiregiaF.MalaiseO.NeuvilleS.PlenerZ.et al (2019)