doi: 10.1001/jama.2023.19574
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The information provided here on liraglutide (Saxenda, Victoza) and semaglutide (Wegovy, Ozempic, Rybelsus) is based on publicly available sources regarding costs, insurance coverage, availability, dosing, and patient-reported experiences
Practical strategies that work: Keep a 32-ounce water bottle visible at all times Drink 16 ounces first thing in the morning before eating Set phone reminders every 2 hours to drink Add lemon, cucumber, or mint to water if plain water becomes unappealing Count herbal tea and broth toward your daily fluid goal Avoid drinking 30 minutes before meals and 30-60 minutes after to prevent worsening fullness Signs of dehydration to watch for: dark urine, headaches, dizziness, dry mouth, constipation worsening, and fatigue beyond what the medication normally causes
Water accelerates peptide degradation through hydrolysis
Eat smaller, more frequent meals rather than large portions, and choose bland, easily digestible foods such as toast, rice, bananas, and plain chicken