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Per USP General Chapter (Aerosols, Nasal Sprays, Metered-Dose Inhalers, and Dry Powder Inhalers), the acceptance criteria require that at least 9 of 10 tested doses fall within 75125% of the labeled dose, with none outside the range of 65135%

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This has slowed to 45 days by the time a person is in their 40s, and it keeps slowing as they become older