Currently, GLP-1 agonist molecules are also prescribed off-label for obesity conditions
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The results of clinical trials indicate that this may make it more effective for weight loss when compared to otherapproved drugs like Wegovy (semaglutide), which targets one hormone, and Mounjaro (tirzepatide), which targets two
At 48 weeks, 93% of participants taking 12 mg achieved normal liver fat levels (below 5%), with an average 86% reduction in liver fat from baseline
Confounding factors further complicate interpretation
GLP-1s may be a worthwhile investment, but their value depends on how they are implemented and supported