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The broader receptor profile of these newer-generation GLP-1 receptor agonists is thought to offer clinical advantages, potentially providing better tolerability or enhanced effectiveness due to simultaneous modulation of reward-related neural circuits and metabolic pathways (Ray 2023

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Lancet Diabetes Endocrinol (2015) 3(4):28695

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[DOI] [PubMed] [Google Scholar] 15.Bolinder J., Ljunggren O., Kullberg J., et al

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Thiazide diuretics, like hydrochlorothiazide, have been associated with a slight increase in serum cholesterol and triglyceride concentrations

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Available from: USDA FoodData Central

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The efficacy and safety of setmelanotide in individuals with Bardet-Biedl syndrome or Alstrom syndrome: phase 3 trial design

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