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TMAO leads to atherosclerosis by changing how cholesterol breaks down, turning on inflammatory pathways, and helping foam cells form [18]

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However, in people with T2D and MASLD, 24 weeks of efinopegdutide 10 mg reduced liver fat content by 72.7% compared to 42.3% reduction with semaglutide 1 mg despite similar WL achieved with both interventions [79]

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