13, article 934695, 7 July 2022, PubMed Central, Abdalqadir, Nyan, and Khosrow Adeli
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It's perfect for addressing wrinkles, loss of elasticity, sun damage, and uneven tone
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Beyond FSP1 there are therapeutic opportunities across the CoQ 10 oxidoreductase network While FSP1 currently has the strongest targetability signal, other CoQ 10 oxidoreductases may be therapeutically leveraged in defined genetic, metabolic or tissue contexts: (1) DHODH axis (mitochondrial defense in select contexts): DHODH connects pyrimidine synthesis to mitochondrial CoQ reduction, and in some settings, DHODH inhibition has been proposed to heighten ferroptosis sensitivity, especially in GPX4-low states
This results in a more even, radiant tone rather than an artificial lightening effect