Compound tirzepatide starts working immediately, but it can take between 10 and 12 weeks for you to see the full effects
Further innovation is seen in triple agonists such as retatrutide, which targets GIP, GLP-1, and glucagon receptors to amplify metabolic effects
They work to stimulate insulin release, inhibit glucagon release, slow the speed of gastric emptying, and reduce appetite by increasing satiety
One trial for the weight loss indication lasted 68 weeks and found that the group taking the drug lost significantly more weight than placebo
Semaglutide targets GLP-1 receptors, while Tirzepatide targets both GLP-1 and GIP receptors
Dose: 17-20 mg/kg is advised for dogs and of 200 mg/day in cats using bioavailable enteric coated tablets given on an empty stomach