Overall, they are considered well tolerated for most people
If you're managing a complex medical history, discuss with your primary care provider before pursuing any GLP-1 program
The benefits of GLP-1 medications in (overweight or obese) women with PCOS may include: While we need more research on GLP-1s and fertility in non-PCOS populations and women seeking fertility treatments, there is ample evidence for women with PCOS using GLP-1 medications for weight loss that the benefits extend to fertility as well
Weight Reduction Mechanisms and Outcomes The weight-reducing effects of GLP-1 RAs are primarily attributed to reduced food intake rather than increased energy expenditure
However, medicines such as semaglutide and liraglutide have been extensively investigated, and a majority of the adverse effects of GLP-1 medications are similar and mainly gastrointestinal 1
So its a mix of metabolic stress and then this relative caloric protein deficiency that happens. Rossi said the problem is becoming more common as the medications are increasingly used by people seeking cosmetic weight loss and who may not be getting adequate nutrition
