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For example, specific GLP1R genetic variants correlate with heightened nausea susceptibility and increased risk of severe gastrointestinal adverse events

(2013) PNAS, 110(22):90669071 Depommier C, Everard A, Druart C, et al

Another study found that over about a year and a half, those taking semaglutide lost around 14% of their body weight on average, compared to only about 2% weight loss for those taking a placebo

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