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Preclinical data show this additive-to-synergistic interaction: each pathway potentiates the other's pituitary response, producing larger GH pulses without proportionally increasing side effects

Gut surgery, pancreatic insufficiency, small intestinal bacterial overgrowth (SIBO), parasite infections, and certain autoimmune disorders are considered additional risk factors

J., Cardiff Symposium on MRS of GABA, & Edden, R

Months 3-6 and beyond: Continued improvement and maintenance Improvement typically continues beyond the 12-week point, though the rate of change slows compared to the initial phase