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Huppke P, Weissbach S, Church JA, Schnur R, Krusen M, Dreha-Kulaczewski S, Kuhn-Velten WN, Wolf A, Huppke B, Millan F, et al

Its health benefits-spanning cardiovascular, neurological, metabolic, and anti-inflammatory domains-are primarily mediated through antioxidant, anti-inflammatory, pro-apoptotic, and signaling pathway modulation mechanisms, as summarized in Table 1

Since ACTH signals the adrenal glands to produce cortisol, reducing ACTH translates to lower cortisol output

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