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261 In addition, the H19 sponge cell miR-130a induces PPAR nuclear translocation, thereby activating the transcription of adipogenic genes like those encoding acetyl coenzyme a carboxylase 1 (ACC1), fatty acid synthase (FAS), and cytochrome c oxidase (SCO1), thereby promoting intracellular lipid accumulation

J Pub Health 32:219-229, 2010

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Contributing author: Martin Schain, PET Imaging Director @ Antaros Medical While the concept of incretins has been around for a while, interest has grown significantly in recent years with the demonstrated efficacy and regulatory approvals of incretin-based therapies for the treatment of both diabetes and obesity