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M., Walton, Z

Diminished oral function is a major risk factor for malnutrition and sarcopenia (Dibello et al., 2021)

These agents have both hormonal and brain targets

FDA-approved alternatives like semaglutide (10-15% loss), tirzepatide (15-22% loss), and CagriSema (15-25% loss) offer comparable or superior results with proven long-term safety profiles, cardiovascular benefits rather than risks, and legal medical oversight

Data available so far suggest that HFDs are associated with a reduction in intestinal bacterial diversity, changes in membrane integrity and the immune system, and low-intensity systemic inflammation