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Diabetes Care 33 , 15911597 (2010)

Clinical research has evaluated doses up to 12 mg per week, depending on individual tolerance and treatment goals

Clinical data shows average weight loss of 1-2 pounds per week during the first 3 months, with pace often slowing thereafter as the body reaches new equilibrium points

Preparing an NDA typically takes 4 to 6 months after the last pivotal trial reports

Federal regulators have agreed to review the applications from Swiss pharmaceutical company Sandoz for two cheaper generic versions of the tirzepatide medications Zepbound and Mounjaro

The most common side effects include nausea, vomiting, diarrhoea, decreased appetite, constipation, stomach pain, and indigestion, and these tend to be most noticeable during the initial weeks of treatment or shortly after a dose increase, typically easing as the body adjusts