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Whilst significant improvement is possible, complete reversal depends on the underlying cause

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These complications not only endanger patients' lives and health but also impose a significant economic burden on families and society

One trial showed improved peak walking times and decreased pain

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NICE guidance (NG28 for type 2 diabetes) recommends that patients on GLP-1 receptor agonists should have regular follow-up to monitor treatment response, tolerability, and the development of adverse effects