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The intermediate stabilization period (months 2-4) represents critical window where post-treatment outcomes crystallize revealing whether improvements prove durable or continue declining toward complete baseline return

[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Napolitano G., Fasciolo G., Di Meo S., Venditti P

TrxR utilizes NADPH to reduce Trx, reducing target proteins through its conserved thiol groups, thereby maintaining cellular redox balance

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glutathione plays an important role in protecting living cells from toxicity by detoxifying the reactive intermediates via enzymatic conjugation