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Once the needle is in place, the treatment is generally painless

Identification of catalytic nucleophile of Escherichia coli -glutamyltranspeptidase by -monofluorophosphono derivative of glutamic Acid: N-terminal Thr-391 in small subunit is the nucleophile

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Similarly, Dings research team engineered a system linking two shRNA transcription plasmids targeting MDR-related genes (P-glycoprotein and survivin) to doxorubicin (DOX)-loaded DNA origami via disulfide bonds [57]