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Some immediate tightening is visible at the time of the procedure a direct result of the subdermal tissue contraction

If you have any of the following conditions, you should not take it: A personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) A history of pancreatitis or severe gastrointestinal issues like gastroparesis Severe kidney disease, since the medication can increase the risk of dehydration Allergies to tirzepatide or any other components of the medication If youre pregnant or planning to become pregnant If you are breastfeeding, there isnt enough data to know if Zepbound passes into breast milk Always discuss your complete medical history with your provider to make sure Zepbound is a safe choice for you

doi: 10.1016/j.freeradbiomed.2024.03.024 92 GuoYZhangHZhaoZLuoXZhangMBuJet al

The start low and go slow dosage changes are frustrating, but will reduce the risk of semaglutide fatigue

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Rapid weight loss associated with semaglutide may paradoxically increase gallstone formation risk, as noted in FDA prescribing information