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Discussion 1) The results of this study completed by McCoy et al systematically evaluated the metabolic stability, BBB permeability, procognitive activity, and synaptogenic potential of Dihexa and other Nle-AngIV analogs, ultimately aiming to identify a therapeutic agent for dementia

This 2022 study is not the first and only such investigation into genes unique to cavaliers and tied to the breed's hereditary mitral valve disease

R = 0.703, p = 0.005, respectively)

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