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Morroniside, a secoiridoid glycoside from Cornus officinalis, attenuates neuropathic pain by activation of spinal glucagon-like peptide-1 receptors
Due to differences in their distribution in tissues or cells and differences in known substrates, it is not known whether GPX family members can complement each other
AtGHR4 appears only to be down-regulated during germination
In this respect, we classify GPx1 as an antioxidant enzyme : by preventing the build up of H2O2, it protects us against a type of cell damage called oxidative damage
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Apart from their catalytic role in protecting cells against xenobiotics, GST isoenzymes can function in the detoxification of chemotherapeutic agents, initiating the development of drug resistance through the inactivation of the anticancer compounds via GSH conjugation (Hayes and Pulford 1995
