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To minimize discomfort, a numbing solution is applied before making small, precise incisions

Most patients find the injections easy to tolerate, especially with proper technique

Recent studies in both human and animal models, summarized in Table 1 , further provide evidence of the relationship between gut microbiota and PND

It is driven by systemic inflammation, microvascular dysfunction in the coronary arteries, and interstitial fibrosis

We noted that the lung to body weight ratio was indeed elevated in AA-exposed mice compared to PBS and melatonin-only controls, however the extent of this increase was substantially reduced in those mice which received melatonin alongside AA ( Figure 1B )