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Anti-AOD-9604 antibodies were not detected in tested participants

Heijer JMD, Kruithof AC, van Amerongen G, de Kam ML, Thijssen E, Grievink HW, Moerland M, Walker M, Been K, Skerlj R et al (2021) A randomized single and multiple ascending dose study in healthy volunteers of LTI-291, a centrally penetrant glucocerebrosidase activator

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hypselobagri induces oxidative stress which results in the generation of reactive oxygen species in the host Wallago attu , with modulation in the level of essential antioxidant enzymes (GST, SOD, GPx, GR, CAT and LPO)

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