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4 Discussion Over 40 busulfan popPK studies have been reported, of which 68% were developed predominantly in children, from which 69% and 26% of models were developed using first-order elimination and time-varying CL, respectively ( In the final model, busulfan disposition was best described by including NFM allometrically as a body size metric and age-dependent maturation function

In humans a rare POMC-null mutation has been described

Pillich RT, Scarsella G, Risuleo G

Drinking lots of water can also help dilute uric acid levels, making it less likely for uric acid crystals to form

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