However, because GLP-1 slows gastric emptying, its essential to adjust your eating habits and choose foods that support digestion, prevent nausea, and keep you feeling balanced
The results, which were published in the Lancet on Thursday, are very encouraging for the safety and efficacy of orforglipron in people with type 2 diabetes, says Daniel Drucker, an endocrinologist at the University of Toronto, adding that he is awaiting further clinical trial results of the drug in people with obesity
Mechanism of action : GLP-1 is a naturally occurring incretin hormone released by the intestines in response to food intake
Yoshinori Abe advises, "GLP-1 users should track body composition, waist size, strength, and metabolic labs rather than weight or BMI alone, since BMI cannot show fat versus muscle." Pay attention to your physical strength as well
Across the three pivotal trials, peak mean body-weight reductions rank retatrutide 12 mg at 24.2% (48 weeks, Phase 2), tirzepatide 15 mg at 22.5% (72 weeks, Phase 3), and semaglutide 2.4 mg at 14.9% (68 weeks, Phase 3) [1][2][5]
If youre considering one, talk to your provider about your health goals, medical history, and coverage options
